| Estepona vs Atletico Central Seville 11 oct | 2.5 | 2.01 / 1.95 | 5 | over |
| Guadalajara S.A.D. vs Getafe B 11 oct | 2.5 | 1.89 / 1.91 | 5 | over |
| Gimnastica Segoviana vs Real Valladolid B 11 oct | 2.5 | 1.84 / 1.83 | 2 | under |
| CS Puertollano vs RSD Alcalá 11 oct | 2.5 | 2.06 / 2.13 | 0 | under |
| CF La Nucía vs Lorca Deportiva 11 oct | 2 | 1.76 / 1.76 | 4 | over |
| UB Conquense vs Albacete Balompié B 11 oct | 2.5 | 2.01 / 2.14 | 4 | over |
| Tudelano vs Reus Reddis 11 oct | 2.5 | 2.06 / 2.06 | 4 | over |
| UE Olot vs Terrassa 11 oct | 2 | 1.81 / 1.91 | 2 | push |
| Mijas Las Lagunas vs Sevilla Atlético 11 oct | 2.5 | 2.04 / 2.04 | 4 | over |
| Atletico Sanluqueno vs Recreativo de Huelva 11 oct | 2 | 1.66 / 1.58 | 6 | over |
| Ciudad de Lucena vs Don Benito 11 oct | 2 | 1.66 / 1.79 | 6 | over |
| CD Badajoz vs FC Marbella 11 oct | 2.5 | 1.95 / 1.93 | 1 | under |
| Arosa vs Bergantiños 11 oct | 2.5 | 1.97 / 1.97 | 4 | over |
| BC Murcia vs CD Alcoyano 11 oct | 2 | 1.76 / 1.76 | 2 | push |
| Real Ávila CF vs Numancia 11 oct | 2 | 1.74 / 1.74 | 2 | push |
| Navalcarnero vs Atlético de Madrid C 11 oct | 3 | 2.09 / 2.16 | 2 | under |
| Coruxo vs Compostela 11 oct | 2.5 | 2.11 / 2.14 | 1 | under |
| Cieza vs Intercity Alicante 11 oct | 2.5 | 2.17 / 1.99 | 4 | over |
| Girona B vs Espanyol B 11 oct | 2.5 | 1.95 / 1.73 | 3 | over |
| Las Palmas B vs Tenerife II 11 oct | 2.5 | 1.84 / 1.81 | 2 | under |
| Las Palmas B vs Tenerife II 11 oct | 2.5 | 1.81 / 1.81 | 2 | under |
| Real Oviedo B vs Rayo Cantabria 11 oct | 2.5 | 1.97 / 1.78 | 3 | over |
| Linares Deportivo vs CA Antoniano 11 oct | 2 | 1.66 / 1.66 | 3 | over |
| Puente Genil vs Tamaraceite 11 oct | 2.5 | 2.13 / 2.06 | 1 | under |
| UD Poblense vs Castellón II 11 oct | 2.5 | 1.93 / 1.79 | 3 | over |
| CD Atlético Baleares vs Mallorca II 11 oct | 2.5 | 1.97 / 1.97 | 4 | over |
| Unión Deportiva Logroñés II vs UD Barbastro 11 oct | 2.5 | 2.13 / 2.06 | 3 | over |
| Deportivo Alavés B vs Gernika Club 11 oct | 2 | 1.66 / 1.61 | 2 | push |
| Real Madrid III vs SD Atlético Tordesillas 11 oct | 2.5 | 1.97 / 1.93 | 0 | under |
| Club Deportiva Minera vs UD Castellonense 11 oct | 2.5 | 2.06 / 2.06 | 5 | over |
| SCR Pena Deportiva vs Orihuela 11 oct | 2.5 | 1.86 / 1.83 | 4 | over |
| Real Murcia II vs Yeclano Deportivo 11 oct | 2 | 1.69 / 1.78 | 2 | push |
| CF Talavera vs CD Atlético Paso 11 oct | 2.5 | 2.10 / 2.14 | 3 | over |
| Salamanca UDS vs San Sebastián de los Reyes 10 oct | 2 | 1.71 / 1.71 | 5 | over |
| FC Sestao Río vs Gimnastica de Torrelavega 10 oct | 2.5 | 2.04 / 2.04 | 0 | under |
| UD Llanera vs Marino de Luanco 10 oct | 2.5 | 2.00 / 1.97 | 6 | over |
| CE Manresa vs Osasuna B 10 oct | 2.5 | 2.01 / 2.00 | 0 | under |
| Naxara vs Pena Sport 10 oct | 2.5 | 1.93 / 1.97 | 1 | under |
| Real Betis B vs Xerez CD 10 oct | 2.5 | 2.13 / 1.83 | 2 | under |
| SD Amorebieta vs Club Portugalete 10 oct | 2.5 | 2.13 / 2.14 | 3 | over |
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