| Gazte Berriak vs Doneztebe 04 oct | 2.5 | 1.91 / 1.91 | 1 | under |
| Calasancio vs Casalarreina Club de Fútbol 04 oct | 2.5 | 1.72 / 1.73 | 3 | over |
| CD Derio vs Beasáin 04 oct | 2.5 | 2.14 / 2.14 | 2 | under |
| Unio Esportiva Vilassar de Mar vs CE Europa II 04 oct | 2.5 | 2.07 / 2.01 | 7 | over |
| Malaga Juniors vs Marbelli 04 oct | 2.5 | 2.12 / 2.12 | 1 | under |
| San Sebastian de los Reyes II vs Real Aranjuez 04 oct | 2.5 | 2.15 / 2.15 | 8 | over |
| Cotillas vs Bala Azul 04 oct | 2.5 | 2.22 / 2.22 | 3 | over |
| Buñol vs Torrent 04 oct | 2.5 | 2.27 / 2.27 | 1 | under |
| UD Santa Marta vs Cultural y Deportiva Leonesa II 04 oct | 2.5 | 2.14 / 2.14 | 2 | under |
| Estradense vs Boiro 04 oct | 2.5 | 2.19 / 2.19 | 5 | over |
| Atlético Saguntino vs Utiel 04 oct | 2.5 | 2.18 / 2.18 | 5 | over |
| Ontinyent 1931 vs Villarreal C 04 oct | 2.5 | 2.24 / 2.18 | 3 | over |
| Chiclana de la Frontera vs Sevilla C 04 oct | 2.5 | 2.11 / 2.11 | 2 | under |
| Alcantarilla vs Atlético Santa Cruz 04 oct | 2.5 | 2.26 / 2.26 | 2 | under |
| UE Porreres vs Santanyi 04 oct | 2.5 | 1.92 / 1.99 | 1 | under |
| CD Quintanar del Rey vs CD Villa de Don Fadrique 04 oct | 2.5 | 1.91 / 1.91 | 2 | under |
| La Calzada vs Comillas 04 oct | 2.5 | 1.84 / 1.76 | 1 | under |
| CA Bembibre vs La Virgen del Camino 04 oct | 2.5 | 2.26 / 2.42 | 2 | under |
| La Almunia vs Cuarte 04 oct | 2.5 | 2.30 / 2.30 | 4 | over |
| UD Vall De Uxo vs Atzeneta 04 oct | 1.5 | 1.50 / 1.50 | 2 | over |
| Recreativo de Huelva B vs Xerez Deportivo FC 04 oct | 2.5 | 2.07 / 2.07 | 2 | under |
| Agoncillo vs Club Atlético Vianés 04 oct | 2.5 | 1.75 / 1.69 | 2 | under |
| Selaya vs Naval Reinosa 04 oct | 2.5 | 1.95 / 2.01 | 5 | over |
| PE Sant Jordi vs Inter Ibiza 04 oct | 2.5 | 1.89 / 2.04 | 0 | under |
| Gran Pena vs Atlético Arteixo 04 oct | 2.5 | 1.91 / 1.79 | 5 | over |
| Castro vs Tropezon 04 oct | 2.5 | 2.19 / 2.19 | 2 | under |
| Haro Deportivo vs Anguiano 04 oct | 2.5 | 1.89 / 1.89 | 3 | over |
| Galapagar vs AD Cala Pozuelo 04 oct | 2.5 | 1.82 / 1.78 | 4 | over |
| Atletico Levante UD vs Crevillente Deportivo 04 oct | 2.5 | 1.90 / 1.84 | – | – |
| Marino vs Playas de Sotavento 04 oct | 2.5 | 1.91 / 1.81 | 7 | over |
| Covadonga vs Club Siero 04 oct | 2.5 | 1.64 / 1.64 | 3 | over |
| UD Montijo vs Jaraiz 04 oct | 2.5 | 2.09 / 2.09 | 2 | under |
| Astur vs Mosconia 04 oct | 2.5 | 2.06 / 2.06 | 0 | under |
| Deportivo Alavés III vs Sodupe UC 04 oct | 2.5 | 1.93 / 1.93 | 6 | over |
| Palencia CA vs Unionistas de Salamanca CF II 04 oct | 2.5 | 2.04 / 2.04 | 3 | over |
| Ibiza Islas Pitiusas vs SD Formentera 04 oct | 2.5 | 2.11 / 2.11 | 2 | under |
| Montanesa vs L'Escala 04 oct | 2.5 | 2.00 / 2.00 | – | – |
| Sporting Gijón B vs Langreo 04 oct | 2.5 | 1.99 / 1.99 | 2 | under |
| Huétor Vega vs Atletico Mancha Real 04 oct | 2.5 | 2.21 / 2.21 | 3 | over |
| Alhaurino vs UD Melilla 04 oct | 2.5 | 1.97 / 1.97 | 3 | over |
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