| 03 oct | Panama City – Chorrillo | 2–1 | 2.32 → 2.59 | 2.89 → 2.90 | 3.35 → 2.90 |
| 02 oct | Rayados de Chiriqui – Union Cocle (r) | 0–0 | 1.71 → 1.75 | 3.90 → 3.29 | 4.26 → 5.04 |
| 02 oct | CA Independiente Reserves – Herrera Panamá | 0–0 | – | – | – |
| 02 oct | Independiente de la Chorrera (r) – Herrera (r) | 0–0 | 1.11 → 1.11 | 7.37 → 7.45 | 25.94 → 26.89 |
| 02 oct | Academia Costa del Este – Tauro (r) | 2–3 | 1.69 → 1.69 | 3.48 → 3.48 | 5.09 → 5.09 |
| 02 oct | AF Sporting San Miguelito II – CD Plaza Amador Reserves | 0–4 | – | – | – |
| 02 oct | Arabe Unido B – San Martin FC | 7–0 | – | – | – |
| 02 oct | Sporting San Miguelito (r) – Plaza Amador (r) | 0–4 | 3.15 → 3.15 | 3.15 → 3.15 | 2.27 → 2.27 |
| 02 oct | Arabe Unido (r) – FC San Martin | 7–0 | 1.63 → 1.63 | 3.46 → 3.46 | 5.78 → 5.78 |
| 01 oct | Alianza Panama (r) – UMECIT (r) | 0–0 | 2.60 → 2.53 | 3.06 → 3.10 | 2.75 → 2.79 |
| 01 oct | Alianza FC II – Umecit II | 0–0 | – | – | – |
| 01 oct | San Francisco FC B – Universidad Latina B | 1–0 | – | – | – |
| 01 oct | SD Atletico Nacional – La Familia FC | 2–1 | – | – | – |
| 30 sept | Potros del Este – Champions FC Academy | 1–1 | – | – | – |
| 30 sept | Potros Del Este – Champions Academy | 1–0 | 1.51 → 1.59 | 3.69 → 3.49 | 7.17 → 6.26 |
| 27 sept | Arabe Unido B – CD Plaza Amador Reserves | 0–1 | – | – | – |
| 27 sept | La Familia – San Francisco (r) | 1–2 | 5.68 → 5.68 | 4.33 → 4.33 | 1.50 → 1.50 |
| 27 sept | La Familia FC – San Francisco FC B | 1–2 | – | – | – |
| 26 sept | San Martin FC – Panama City FC | 0–2 | – | – | – |
| 26 sept | FC San Martin – Panama City | 0–2 | 3.46 → 3.46 | 3.51 → 3.51 | 1.99 → 1.99 |
| 26 sept | Universitario (r) – UDELAS | 0–1 | – | – | – |
| 26 sept | SD Rayados de Chiriquí FC – CA Independiente Reserves | 0–2 | – | – | – |
| 26 sept | Universidad Latina B – Udelas FC | 0–1 | – | – | – |
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